Two years later: the ” ice bucket challenge “it worked, all right

A research group funded with money from the 2014 viral phenomenon has identified a gene, NEK1, that could be the key to a future cure

In the end it was not useless to the bucket of ice water on his head, l ‘ “ice bucket challenge” that has marked the summer of 2014, documented 17 million videos on YouTube made the center. Two years later, the original fund-raising campaign launched by the ALS Association of the United States against amyotrophic lateral sclerosis has paid off: thanks to the $ 200 million collected (115 in the first six weeks), six were activated programs research involving 80 researchers from 11 countries.

In particular was the Project MinE to get a hit. The group led by the University of Massachusetts and the Utrecht University Medical Center has earned more excellent results, isolating for the first time a gene, the NEK1, involved in neurodegenerative processes that affect patients. The researchers of the Project MinE found that in a sample group of 1,022 people who had inherited ALS, 3% had mutagenic of NEK1.

Understand the operation of NEK1 gene, which contributes to the energy supply of neurons, and repair of DNA, it is a step in the direction of the cure. The causes of ALS remain unknown, but a 10% correspondence has been observed in consanguineous that indicates that the genes are at least partly responsible for the pathology. Italy has contributed to the project with two scientific studies published in the journal Nature Genetics signed by the researchers of the Institute Auxologico, Vincenzo Silanes and Nicola Ticozzi. Thanks to social networks, even in Italy thousands of people had responded to the appeal by agreeing to roversciarsi him, for good, a water and ice bucket. Who could pass the test had to “appoint” others to do likewise. Among many others, also attended by Prime Minister Matteo Renzi.

Margot Robbie, after Harley Quinn another crazy role in Bad Monkeys

Now little lacking at his trial as a criminal-loving Joker in Suicide Squad, meanwhile, the actress has already decided his next character: again, sanity is very challenged …

It seems that Margot Robbie we’ve taken a liking, with the roles of crazy. While the movies we see it as a companion of Tarzan, in the very short (Suicide Squad comes out August 13) will appear on the big screen in the role of Harley Quinn, dangerous criminal in love with the Joker.

According to the Hollywood Reporter, he is already prepared another by crowds role: it is Bad Monkeys, film adaptation of the novel by Matt Ruff whose Robbie will also be producing.

She will play the heroine Jane Charlotte, arrested for murder by the police claiming to act on behalf of a secret society, the Bad Monkeys, whose task is to rid the world of evil. The woman obviously will be deemed insane and interned in a psychiatric hospital, where he will continue to behave as such, although some will rise the doubt …

If Margot Robbie will be credible as it is Harley Quinn – at least judging by the trailer -, it can bet that even in the thriller will be crazy good try!

When men become Mummy for beer

Here are pictures irreverent advertising campaign Bergedorfer Bier, photographing the boys in the most typical of pregnant women positions
Nearly-moms that gently caress your belly, proud of what they are about to give birth we have seen countless. But what would happen if the same attitude was adopted by virilissimi men who take care of your stomach cultivated with blondes and burgers? The answer comes from the new campaign Bergedorfer Bier, created in collaboration with the German advertising agency Jung von Matt.

The promotional photos, which you can browse in our gallery, depicting just a boys team of different ages committed to cuddle with gentleness his beer belly. Mummy of hops, in fact. The slogan of advertising, on the other hand, makes everything clear: “Brewed with love”, prepared with love. That of toast with friends, definitely. Besides, you know, the perfect male – women say – is that who is not afraid of the handles on the sides.